CD40LG

CD40LG
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1ALY, 1I9R, 3LKJ, 3QD6
Dynodwyr
Cyfenwau	CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L, CD40 ligand
Dynodwyr allanol	OMIM: 300386 HomoloGene: 56 GeneCards: CD40LG
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• cytokine activity; • CD40 receptor binding; • tumor necrosis factor receptor binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • integral component of plasma membrane; • extracellular region; • external side of plasma membrane; • intracellular anatomical structure; • cell surface; • extracellular space;
Prosesau biolegol	• leukocyte cell-cell adhesion; • positive regulation of interleukin-12 production; • negative regulation of apoptotic process; • tumor necrosis factor-mediated signaling pathway; • platelet activation; • positive regulation of endothelial cell apoptotic process; • B cell proliferation; • isotype switching; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response; • regulation of immune response; • B cell differentiation; • inflammatory response; • T cell costimulation; • positive regulation of NF-kappaB transcription factor activity; • positive regulation of interleukin-4 production; • positive regulation of interleukin-10 production; • positive regulation of T cell proliferation; • regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologau
	959
	n/a
	ENSG00000102245
	n/a
	P29965
	n/a
	NM_000074
	n/a
	NP_000065
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD40LG yw CD40LG a elwir hefyd yn CD40 ligand (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq26.3.^[2]

[1] "Human PubMed Reference:".

[2] CD40LG - Cronfa NCBI

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